T4 DNA Ligase (HC), 500u Item ID: PMM1794

enzyme,cloning,ligase,c126,m180,m179

For ligation of DNA ends.

T4 DNA Ligase catalyzes the joining of two strands of DNA between the 5'-phosphate and the 3'-hydroxyl groups of adjacent nucleotides in either a cohesive-ended or blunt-ended configuration. The enzyme has also been shown to catalyze the joining of RNA to either a DNA or RNA strand in a duplex molecule but will not join single-stranded nucleic acids.