A recent publication on reprogramming fibroblasts into induced pluripotent stem cells using the Seahorse extracellular flux analyser identified that nuclear reprogramming efficiency might be improved by modulating mitochondrial spare capacity. Namely, cells with lower spare respiratory capacity produce iPSCs at higher efficiencies.
Discover how these metabolic measurements can be used as indicators to minimise workflow inefficiencies and improve differentiation and reprogramming approaches.
Signaling pathways that control cell proliferation and differentiation are important targets for small molecules in the culture of stem cells. Targeting pathways can be useful to enhance and maintain the proliferation of stem cells, or to guide stem cell fate toward specific lineages in controlled differentiation.
Depend on Tocris for:
|Authentic Stem Cell Compounds: Highly qualified in-house chemistry and analytical teams ensure each product is manufactured to the highest purity possible, so you can trust your product is authentic and can publish with confidence.|
|Consistently High Quality: The Tocris analytical team perform stringent quality control analysis not done by other suppliers, ensuring batch-to-batch consistency.|
|Guaranteed Resupply: Tocris has >99.5% of products in stock at all time, offering you a guaranteed supply of product for your experiments and publications.|
|Innovative Product Range: Tocris are continually adding to their wide range of new and innovative research tools.|
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