Stem Cell Culture
Stem cell research provides a lens into the mechanisms of developmental biology and serves as a powerful tool for disease modelling, drug discovery, and the creation of regenerative therapies.
Stem cells are defined by their unique ability to self-renew and differentiate into intermediate and terminal cell types. Each stem cell type requires specialized growth conditions for expansion and differentiation in vitro, relying on defined serum-free medium, combinations of growth factors, and specific adhesion molecule interactions.
Advances in stem cell biology have revealed that small molecules and transcription factors alone can be used to reprogram stem cells or directly induce their differentiation into terminal somatic cells.
Choose Quality Stem Cell Reagents
R&D Systems supports all aspects of stem cell culture by producing media, extracellular matrices, differentiation kits, growth factors, and small molecules. Consistent, high-quality reagents minimize variability in your research, allowing you to culture with confidence.
Listen to Stem Cell Core Facility Directors describe why they use R&D Systems proteins and small molecules for their cultures.
Induced Pluripotent Stem Cells
- ExCellerate™ GMP iPSC Expansion Media
- Cultrex™ Basement Membrane Extracts and ECM Proteins
- Cytokines and growth factors
- StemXVivo™ differentiation kits
- Small molecules for reprogramming
- Non-viral gene transfer with TcBuster™
Embryonic Stem cells
- Compounds for ESC research
- ESC & iPSC differentiation kits & reagents
- ESC & iPSC culture kits & Reagents
- Compounds for ESC/iPSC proliferation
- ESC markers
Hematopoietic Stem Cells
- HSC media and supplements at R&D Systems
- Lineage depletion antibody panels at R&D Systems
- HSC multicolor flow cytometry kit
- Methylcellulose reagents for CFC assays
- Cytokines and growth factors, including Flt-3 Ligand, IL-3, SCF, and Thrombopoietin
- Hematopoietic Stem Cell Markers
- Small molecules for HSC research at Tocris
Mesenchymal Stem Cells
- StemXVivo™ MSC media and supplements
- Small molecules for MSC differentiation
- Functional identification kits for MSC
- Cytokines and growth factors
- Non-viral gene transfer with TcBuster
- Learn about MSC markers and MSC function
Neural Stem Cells
N-2 and N21 supplements
- Differentiation kits for dopaminergic neurons and oligodendrocytes
- Functional identification kits
- Imaging dyes
- Cytokines and growth factors
- Small molecules for NSC differentiation
- Learn about NSC Markers
Cancer Stem Cells
- CSC identification antibodies at R&D Systems
- Cultrex™ tumor spheroid assays
- Cultrex™ cell migration and invasion assays
- EMT induction supplement and 3-color IHC kit
- Cancer stem cells markers
CEPT Cocktail for Improved Cell Survival
Improve stem cell survival with our small molecule CEPT cocktail. A combination of 4 small molecules, Chroman 1, Emricasan, Lyophilized Polyamine Supplement and Trans-ISRIB, the CEPT cocktail enhances the viability of stem cells during passaging, single cell cloning, gene-editing, cryopreservation, and differentiation and can be used in the manufacture of organoids for use in disease modeling or drug screening.
Stem Cell Resources
Explore resources to support your stem cell research. From application notes and guides to webinars and posters, our resources are crafted to provide valuable knowledge and propel your research forward.
Product Guides
Application Notes
Webinars
iPSC Best Practices Webinar
Hear about the best practices for iPSC culture and differentiation from Dosh Whye, Assistant Director at Boston Children's Hospital.
iPSC to Beta Islet Symposium
A panel of field experts comes together to discuss their research plus connect it back to those it will impact most.
iPSC to Neural Cells & Organoids
Watch on-demand to learn how iPSCs have changed neural research from Dr. Dan Cortes, iPSC Cell Culture Manager at HHMI.
