RNA Interference Tools | abm

Applied Biological Materials (ABM) provides a comprehensive suite of RNA Interference Tools, including synthetic siRNAs and vector-delivered siRNA constructs designed for efficient, sequence-specific gene knockdown.

If stable and long-term modulation is required, abm’s miRNA lentiviral vectors enable controlled overexpression or inhibition of endogenous miRNA pathways, offering precise regulation of post-transcriptional gene silencing.

These systems are widely used for dissecting gene function, validating targets, and probing regulatory circuits in development, metabolism, and disease.

Together, these tools give researchers a reliable, flexible platform for gene knockdown and miRNA pathway modulation, ensuring reproducible silencing across a broad range of mammalian systems.

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Publication 1

Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform, Da Li et al., Nature Communications (2020) read here