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R&D Systems is the world’s premiere source of Cytokines & Proteins. Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. 

At R&D Systems, quality and performance is the number one priority.

R&D Systems’ experience and dedication to protein development and manufacturing is unmatched in the life science industry.

rdstarThe R&D Systems® Quality Advantage


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Please find your products on the R & D Systems website below and then contact us on for local pricing and availability.

rndimages Recombinant Proteins

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For more support in finding products that best fit your research, R&D Systems have developed a range of interactive Pathways & Processes which allows you to explore intracellular signaling pathways and biological processes. 

Investigate these signalling pathways

Request a bulk quote for Cytokines and Proteins from In Vitro Technologies:


pdf GMP Grade Proteins

Lot-to-Lot Consistency: Ensuring experiments can always be repeated!

  • For new proteins multiple lots are created, all with matching specifications. This ensures that there will be no problem matching original lots in the future.
  • Each new lot is tested side-by-side with previous lots for purity, biological potency, and endotoxin level.

Biological Activity

  • Proprietary methods for accurate protein folding ensure biologically relevant proteins
  • R&D systems uses over 900 validated bioassays to evaluate recombinant proteins bioactivity
  • Bioactivity is measured experimentally with the appropriate biological system.

Endotoxin Level and Microbial Bioburden Test

  • Each new production lot of protein is assessed for endotoxin using the Limulus Amoebocyte Lysates (LAL) assay. The endotoxin specification is an industry-leading <0.1 EU/ug.
  • Each protein is tested to rule out microbial contamination using direct plating and broth dilution, according to guidelines from the United States Pharmacopeia (USP).

Protein Sequence Accuracy

  • N-terminal amino acid sequence analysis is performed for each recombinant protein to verify the protein produced matches the sequence expected


  • Recombinant proteins are formulated for best stability and are lyophilized from a sterile filtered solution. They are available without or with a carrier protein, usually bovine serum albumin (BSA) at 50 mg/mg of protein.
  • Recombinant enzymes are in solution and ready to use