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The New Minifors 2

blog productThe new Minifors 2 benchtop bioreactor from Infors-HT is simple and easy to operate and is a great a starting point for people new to fermentation. The Minifors 2 is a compact, easy-to-use bioreactor with a full range of application possibilities. It is a complete package that enables both beginners and experienced users to easily perform microbial applications.

The Minifors 2 comes as a complete package with everything you will need for the culture of microorganisms. The fully equipped culture vessel is located on a compact base unit with four freely configurable pumps, pH and pO2 sensors, two fully automatic gas lines with mass flow controllers and a touch screen control unit. Three different and interchangeable culture vessels are available, up to a total vessel volume of six litres.

Handling of the Minifors 2 is simple, with its small footprint and few external connections, the bench-top bioreactor takes up little space in the lab. Your work around the bioprocess will be simplified by special details; for example, the practical vessel holder that enables the safe and risk-free transport of the pump heads and the bottles together with the culture vessel to the autoclave.

Operation of the Minifors 2 is simple; either using the integrated touchscreen control or by connection to an external PC and remote operation with eve, Infors-HT’s bioprocess software. eve covers every aspect of a bioprocess, with a straightforward user navigation system that keeps the workflow on hand at all times. The workflow integrates all of the experimental requirements, from project, experiment and batch planning to resource administration and analysis of the results. Process management is comprehensive and easier than ever before. If the Minifors 2 is controlled autonomously, bioprocess data is easily exported using a USB drive in .csv format.

The Minfors 2 offers excellent performance in an affordable, easy to use package and will help you take your bioprocess further

Features
The Minifors 2 offers features beyond those of other devices of its class. Just go with your bioprocesses – and have fun thanks to optimized handling and ease of use.

Interesting options

eve® can do more than just plan, control and analyse your bioprocesses. The eve® software integrates workflows, devices, bioprocess information and big data in a web-based platform that lets you organise your projects. Thus, you maintain an overview of your projects and can efficiently execute them thanks to extensive monitoring and analysis options.

  • Planning, control and analysis
  • Integrated workflows, devices and bioprocess knowledge
  • Web-based project organization
  • Communication using the latest OPC UA standard
  • Synchronization of process-related events such as sampling or inoculation

More about eve®

  • Analysis of oxygen and carbon dioxide concentrations in the exhaust gas of the bioreactor
  • BlueInOne sensor from BlueSens
  • Connects directly to Minifors 2
  • Additional information gained via eve® soft sensors such as
    • Oxygen Uptake Rate (OUR)
    • Carbon Evolution Rate (CER)
    • Respiratory Quotient (RQ)
  • ASD12-N sensor from Optek
  • Based on IR turbidity measurement from 840 nm to 910 nm
  • Connects directly to Minifors 2 through an integrated transmitter
  • Provides real time information about the biomass concentration without sampling
  • Connection of an external balance possible
  • Use for precise gravimetric feeding possible
  • For advice in choosing appropriate scales, contact your local INFORS HT service partner

Features

infors ht minifors2 kulturgefaesseFully equipped, with great handling – simply practical.

• Available in total volumes of 1.5 L, 3 L and 6 L
• Powerful direct drive of up to 1600 min-1
• Quick and easy change between culture vessel sizes
• Rounded flat vessel bottom
   • Low minimum working volume
   • Good mixing
   • Stability with or without a vessel holder
• Safe sampling without any dead volume: INFORS HT Super Safe Sampler

Minifors 2 brochure including technical data (PDF)

infors ht minifors2 deckelPlenty of room for online analysis.

• Intelligent design for easy access to all ports
• Convenient, tool-free cleaning and maintenance thanks to knurled screws
• Sufficient ports, for standard fittings and extra inlets, immersion tubes and sensors
   • 
4 x 7.5 mm: addition ports available for acid, base, feed & 1 free
   • 
4 x 10 mm: sparger, anti-foam system, temperature sensor, sampling/harvest
   • 
Maximum 7 x 12 mm (Pg13.5): pH, pO2, exhaust gas cooler, inoculation are pre-allocated, 3 are freely available

Minifors 2 flyer including technical data (PDF)

infors ht minifors2 begasungVigorous gassing, fully automated.

• 2 integrated Mass Flow Controllers (MFC)
• Operation with air, air/O2, or air/N2
• Integrated pressure sensor for detecting a blocked filter
• Gassing optimized for bacteria applications: specific gassing rate (vvm) up to 2.0 min-1
• Multiple cascades for pO2 control by means of stirrer speed, gassing rate (“TotalFlow”) and/or gas composition (“GasMix”)

Minifors 2 flyer including technical data (PDF)

infors ht minifors2 pumpenProvide so much more than just precision.

• 4 precision pumps
• Configurable operating mode: digital (fixed-speed) or analogue (variable speed)
• Default setting: 3 x digital (acid, base, anti-foam), 1 x variable (feed)
• Autoclavable pump heads
• Gravimetric feeding possible (requires external balance)
• Profile-based control of pump speed (requires eve®)

Minifors 2 flyer including technical data (PDF)

hamilton sensorsIntelligent, digitally-controlled sensors as standard.

• Robust, digital connection of pH and pO2 sensors
• Optical pO2 sensor: immediately ready for use as no polarization is required
• Storage of calibration data in the sensor head
• Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
• Compatible with Hamilton ARC

Minifors 2 flyer including technical data (PDF)

infors ht minifors2 bedieneinheitNew, different – better: the most intuitive control unit

• Integrated 7″ touch screen (17.8 cm)
• Simple handling through intuitive menus and practical on-screen help
• Calibration of pH, pO2 and OD sensors using simple install wizards
• Direct data export to USB drive in stand-alone operation
• Multiple display languages


Minifors 2 flyer including technical data (PDF)

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The Minifors 2 is for microbial culture, including Escherichia coli, Saccharomyces cerevisiae and Komagataella phaffii (Pichia pastoris). E.coli is used for simple recombinant protein production, while yeasts such as S. cerevisiae and K. phaffi are better able to post-translationally modify mammalian proteins, leading to better yields. All of the following microbes that are typically used for recombinant protein production are available from ATCC and can be cultured in the Minifors 2.

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09.03.2017